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The "Immortal Jellyfish" Can Revert Back to Its Juvenile Stage to Escape Death

Turritopsis dohrnii is the only known animal that can biologically reverse aging. When stressed or injured, it reverts to its juvenile polyp stage and starts life over.

The "Immortal Jellyfish" Can Revert Back to Its Juvenile Stage to Escape Death
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Most animals die. Turritopsis dohrnii — a tiny jellyfish about 4.5 mm across — has a different idea.

When this creature is injured, starving, or otherwise stressed, instead of dying, it performs an extraordinary trick: cellular transdifferentiation. Its mature cells reorganize back into juvenile cells, and the entire organism reverts to its earlier polyp stage. Then it grows up again. And it can do this indefinitely.

Why It's Called Immortal

In theory, a single individual could continue this cycle forever — making it the only known animal capable of escaping biological aging. In practice, most are eaten by predators or succumb to disease before they can demonstrate immortality. But under controlled lab conditions, individuals have rejuvenated themselves repeatedly.

Why Scientists Are Obsessed

  • Understanding cellular reversal could unlock new approaches to age-related disease
  • It challenges the assumption that aging is irreversible at the cellular level
  • It shows that complex multicellular life has more biological options than we thought

The jellyfish has spread worldwide over the past century, hitching rides in ship ballast water. Some scientists call it "the world's only immortal invasion."

Source: Smithsonian Magazine

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